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13 Other concerns are the inhaled effects of flavors and other substances, which remain under investigation

Many young people who use e-cigarettes also smoke real cigarettes

Our model says that more than 15% of consumption in Indiana going forward will be smuggled in as a function of tax evasion and avoidance.[53] Legal sales in Indiana have dropped by 34% from June 2025 (just before the tax hike) through September 2025, according to the consulting firm of Orzechowski and Walker.[54] This information is based on tax-paid stamp sales data it collected from the state

The reduction in HCC risk for ex-smokers compared to current smokers is a powerful incentive for cessation [101]

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